Some follicular lymphomas can also change (transform) into or return as dlbcl. Like most lymphomas, it usually begins in the lymph nodes;
The cancer grows in the b cells, also called b lymphocytes, which make antibodies to attack invading pathogens.
Follicular lymphoma b cell. These lymphomas may not need to be treated when they are first diagnosed. Follicular describes how the lymphoma cells group together in clusters in a lymph node or other tissues. Follicular b cells (fo b cells) are a type of b cell that reside in primary and secondary lymphoid follicles (containing germinal centers) of secondary and tertiary lymphoid organs, including spleen and lymph nodes.
Fl develops when b cells become abnormal (cancerous). Follicular lymphoma is a cancer of the lymphatic system and develops from b lymphocytes (white blood cells that fight infection). Ezh2 activity represses the expression of genes involved in differentiation, negative cell cycle regulation, and apoptosis.
In follicular lymphoma, white blood cells start multiplying abnormally. Common symptoms associated with lymphoma include painless enlargement of one or more lymph node areas, fever, night sweats, and weight loss. It can spread into the blood and bone marrow, as well as the internal organs.
Follicular lymphomas often respond well to treatment, but they are hard to cure. In healthy cells, ezh2 activity is. Some follicular lymphomas can also change (transform) into or return as dlbcl.
Antibody responses against proteins are believed to involve follicular b cell pathways in secondary lymphoid organs. Like most lymphomas, it usually begins in the lymph nodes; White blood cells are also known as b cells or b lymphocytes.
Instead, treatment may be delayed until the lymphoma starts causing problems. Involvement of other lymphatic tissues such as the spleen or bone marrow. Follicular lymphoma is characterized by diffuse lymphadenopathy, bone marrow involvement, and splenomegaly.
When you have follicular lymphoma, the sick blood cells can travel to many parts of your body, such as your organs, bone marrow, and lymph nodes. Follicular lymphoma (fl) is generally an indolent b cell lymphoproliferative disorder of transformed follicular center b cells. These then collect in lymph nodes and elsewhere in the person.
The cancer grows in the b cells, also called b lymphocytes, which make antibodies to attack invading pathogens. It usually occurs in people 50 years of age or older, and the average age at diagnosis is 59.