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There is general consensus that increasing platinum dose intensity in ovarian carcinoma has not been proven. It is possible that certain patients could benefit, and ongoing studies may help identify which ones.
By giving the same doses of.
Dose dense chemotherapy ovarian cancer. Anemia, for example, is one of the most common side effects of cancer. By giving the same doses of. Ddc hopes to kill as much of the tumor as possible.
In the nejm study, patients who received paclitaxel weekly had a higher rate of grade 3. Patients accepted weekly paclitaxel 80 mg/m 2 on day 1, 8, 15 and carboplatin on day1 at area under curve (auc) 6 every 21 days were reviewed for. However, recent studies have explored alternative schedules of this doublet, providing.
It is possible that certain patients could benefit, and ongoing studies may help identify which ones. There is general consensus that increasing platinum dose intensity in ovarian carcinoma has not been proven. Download citation | dose dense chemotherapy in ovarian cancer | in essence, dose densification is accelerated therapy (a commonly used phrase in.
Ongoing studies will clarify the best dose, schedule, and route of administration. 19767094 [indexed for medline] publication types: (1)arizona cancer center, tucson, az 85724, usa.
In essence, dose densification is “accelerated therapy” (a commonly used phrase in radiotherapeutics) and is a form of dose intensification because the amount of drug per unit time (dose intensity = mg/m 2 /week) is increased. The most commonly used weekly dose is 80 mg/m 2 delivered intravenously over 1 h. The actual dose of chemotherapy is not increased, but the time between doses is shortened.